Supplementary Material of the Manuscript
Costs of life - Dynamics of the protein inventory of Staphylococcus
aureus
during anaerobiosis
The shown animation is a space filling Voronoi Treemap based
visualization of the protein inventory of
S. aureus along a growth
experiment with t0 (transfer from aerobically grown exponential phase
culture to anaerobic conditions), t5 (5h anaerobic conditions), t7 (7h
anaerobiosis) and t9 (9h anaerobiosis).
For zooming please use the mouse wheel. The movie shows a sequence of
slides with expression data at t=0h, t=5h, t=7h and t=9h after a shift
of an aerobically grown culture to anaerobic conditions. Expression on
protein level has been encoded in shades of blue with white (no
expression at all) and blue (highest observed expression along the
shown time line). Cell sizes encode the maximum protein amount over
the monitored sampling points t0 to t9.
For the display of the single samples please pause the animation
(PAUSE button left hand side of the time scale) and move the slider
correspondingly. To resume the movie use the PLAY button
correspondingly.
Holding down the hierarchy buttons on the right bottom corner
temporally displays the gene functional assignments of all shown
proteins.
[Here]
the underlying data can be downloaded.
1Institute of Microbiology, Ernst-Moritz-Arndt-University
Greifswald, F.-L.-Jahn-Strasse 15, D-17487 Greifswald, Germany
2Institute of Biochemistry, Ernst-Moritz-Arndt-University
Greifswald, Felix-Hausdorff-Strasse 4, D-17487 Greifswald, Germany
3Department of Mathematics and Informatics,
Ernst-Moritz-Arndt-University Greifswald, Walther-Rathenau-Strasse 47,
D-17487 Greifswald, Germany
4Interfaculty Institute for Genetics and Functional
Genomics, Ernst-Moritz-Arndt-University Greifswald, F.-L.-Jahn-Strasse
15 a, D-17487 Greifswald, Germany
#Current address: Department of Pathology, Boston
Children’s Hospital and Harvard Medical School, and the § Proteomics
Center, Boston Children’s Hospital, Boston, MA, USA
$Current address: Institute of Microbiology, Technical
University Braunschweig, Inhoffenstrasse 7, D-38124 Braunschweig,
Germany
фCurrent address: Robert Koch Institute, FG13 Nosocomial
Pathogens and Antibiotic Resistance, Wernigerode, Germany
*contributed equally